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  Young genes with mutant or insertion stocks

From analysis of the 12 Drosophila species genomes, Zhang et al. (2010) identified 947 young protein-coding genes that were created recently in the lineage leading to D. melanogaster. We listed D. melanogaster stocks that are assigned to 412 "very young" genes.

These "young" genes are classified as 102 retrogenes, 741 DNA-level duplicates, or 104 other newly created protein-coding genes. We listed 412 "very young" genes originated on branches 4 - 6 (see Figure) and stocks that are assigned to these "very young" genes. As for insertion stocks, we selected those that are located within 1-kb of transcriptional region. Stock information was acquired from Kyoto DGRC, NIG-Fly, and FlyBase; mRNA expression data come from FlyAtlas.

phylogenetic tree for young genes branch0 branch1 branch2 branch3 branch4 branch5 branch6

Figure - Age distribution of young protein-coding genes created in the lineage leading to D. melanogaster (Figure 1. of Zhang et al. 2010; Creative Commons License [Attribution-NonCommercial 3.0 Unported License]). Underlined numbers indicate the numbers of young genes originated on branches 0-6. For example, 68 genes were created after divergence of D. yakuba and D. erecta but before divergence of D. simulans and D. sechellia (branch 5).

Zhang YE, Vibranovski MD, Krinsky BH, Long M. Age-dependent chromosomal distribution of male-biased genes in Drosophila. Genome Res. 2010 Nov; 20(11): 1526-1533. doi: 10.1101/gr.107334.110. Epub 2010 Aug 26.

>>> Genes created on branch 4
>>> Genes created on branch 5
>>> Genes created on branch 6

Y. Kanamori & M. Tomaru
Date: 29 March 2013


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