| Strain Information | |
|---|---|
| DGRC Number | 109027 |
| Genotype with FlyBase Link | w[*]; AGO2[414] |
| Genotype | w*; AGO2414 |
| Received Date | 30 June 2004 |
| Also known as | w[*]; AGO2414 |
| Original Source | Haruhiko Siomi, University of Tokushima |
| Original Comments | AGO2414 allele is a null allele, and homozygous AGO2414 mutants can be maintained as a stock. Homozygous AGO2414 mutant embryos are siRNA-directed RNAi defective, and thus that can be used to study the molecular pathways of RNAi. References: K |
| Genus | Drosophila |
| Subgenus | Sophophora |
| Species Group | melanogaster |
| Species Subgroup | melanogaster |
| Species | melanogaster |
| Last update | 2020-04-03 |
| Research papers using this strain [Please submit your publication] |
Fukuda J, Kosuge S, Satoh Y, Sekiya S, Yamamura R, Ooshio T, Hirata T, Sato R, Hatanaka KC, Mitsuhashi T, Nakamura T, Matsuno Y, Hatanaka Y, Hirano S, Sonoshita M. Concurrent targeting of GSK3 and MEK as a therapeutic strategy to treat pancreatic ductal adenocarcinoma. Cancer Sci (2024) [PubMed ID = 38320747] [RRC reference] Phipps DN, Powell AM, Ables ET. Utilizing the FLP-Out System for Clonal RNAi Analysis in the Adult Drosophila Ovary. Methods Mol Biol (2023) 2626 69-87 [PubMed ID = 36715900] [RRC reference] Abe M, Naqvi A, Hendriks GJ, Feltzin V, Zhu Y, Grigoriev A, Bonini NM. Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila. Genes Dev (2014) 28(1) 44-57 [PubMed ID = 24395246] [RRC reference] |
| Stock Request | |