Detailed Information [109096]
 

Strain Information
DGRC Number 109096
Genotype with FlyBase Link w[*]; P{hs-hBtk[E41K]}DY1 / TM6B
Genotype w*; P{hs-hBtkE41K}DY1 / TM6B
Received Date 18 Mar 2005
Comments Ubx like phenotype can be observed. 03Apr2012 M.W.
Original Source Daisuke Yamamoto, Waseda Univ.
Original Comments E41K mutant of human Btk (Bruton's tyrosine kinase) driven by the heatshock70 promoter on II. Btk, when mutated, is responsible for the heritable immunodeficiency, XLA, in humans. E41K mutant is constitutively active in human cultured cells.
Genus Drosophila
Subgenus Sophophora
Species Group melanogaster
Species Subgroup melanogaster
Species melanogaster
Last update 2020-04-03
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