| Strain Information | |
|---|---|
| DGRC Number | 109932 |
| Genotype with FlyBase Link | w[*]; spn27A[1] / CyO, P{w[+mC]=ActGFP}JMR1 |
| Genotype | w*; spn27A1 / CyO, P{w+mC=ActGFP}JMR1 |
| Received Date | 17 February 2014 |
| Original Number | Spn27A25A |
| Chromosome | 1;2 |
| Also known as | w; spn27A25A/Cyo-actin-GFP |
| Original Source | Bruno Lemaitre, École Polytechnique Fédérale de Lausanne |
| Original Comments | Mutaton affecting the melanization and clotting pathway. Null mutation (P element excision) in the serpin 271 gene. Spn27A mutants shows decrease viability at the pupal stage. Spn27A larvae and adults show an excessive melanisation reaction after injury. |
| Genus | Drosophila |
| Subgenus | Sophophora |
| Species Group | melanogaster |
| Species Subgroup | melanogaster |
| Species | melanogaster |
| Reference | De Gregorio E, Han SJ, Lee WJ, Baek MJ, Osaki T, Kawabata S, Lee BL, Iwanaga S, Lemaitre B, Brey PT. An immune-responsive Serpin regulates the melanization cascade in Drosophila. Dev Cell (2002) 3(4) 581-92 [RRC reference] |
| Last update | 2022-05-30 |
| Research papers using this strain [Please submit your publication] |
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| Stock Request | |