Detailed Information [117673]
 

Strain Information
DGRC Number 117673
Genotype with FlyBase Link w[*]; mei-W68[1] / CyO; P{w[+mC]=Hsp83-Atha\SPO11-1.S}A5-1 / TM3, P{ActGFP}JMR2, Ser[1]
Genotype w*; mei-W681 / CyO; P{w+mC=Hsp83-Atha\SPO11-1.S}A5-1 / TM3, P{ActGFP}JMR2, Ser1
Received Date 13 March 2014
Original Number K325.5
Chromosome 1;2;3
Also known as w; mei-W68[1]/Cy; P{w+, hsp83pro-AtSPO11-1-hsp70TT A5-1}/TM3 JMR2
Original Source Kohji Kusano, Kyoto Institute of Technology
Original Comments This transgene is on the 3rd chromosome. A cDNA of Arabidopsis thaliana AtSPO11-1 gene (a homologue of D. melanogaster mei-W68 gene) was cloned into a P-element transformation vector CaSpeR-hsp83, which includes hsp80 promoter and hsp70 terminator as well as a mini-white gene, and transformed. The ectopic expression from this transgene never complemented reduced female fertility of mei-W68[1] homozygotic flies, but showed weak double-stranded break-forming activity.
Genus Drosophila
Subgenus Sophophora
Species Group melanogaster
Species Subgroup melanogaster
Species melanogaster
Reference Shingu Y, Tokai T, Agawa Y, Toyota K, Ahamed S, Kawagishi-Kobayashi M, Komatsu A, Mikawa T, Yamamoto MT, Wakasa K, Shibata T, Kusano K.
The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay.
BMC Mol Biol (2012) 13 1 [RRC reference]
Last update 2020-04-03
Research papers using this strain
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