Detailed Information [118092]
 

Strain Information
DGRC Number 118092
Genotype with FlyBase Link w[*]; Df(2R)PPO2[Delta], PPO2[Delta] TI{w[+mW.hs]=TI}PPO1[Delta] PPO3
Genotype w*; Df(2R)PPO2Δ, PPO2Δ TI{w+mW.hs=TI}PPO1Δ PPO3
Received Date 22 Jun 2017
Original Number PPO1, PPO2, PPO3[1]
Chromosome 1;2
Also known as w[*]; ProPO45,ProPO-A1,PPO3[1]
Original Source Bruno Lemaitre, École Polytechnique Fédérale de Lausanne
Original Comments The fly line lacks the three Drosophila PPO and is not melanized upon septic wounding and encapsulation.
Genus Drosophila
Subgenus Sophophora
Species Group melanogaster
Species Subgroup melanogaster
Species melanogaster
Reference Binggeli O, Neyen C, Poidevin M, Lemaitre B.
Prophenoloxidase activation is required for survival to microbial infections in Drosophila.
PLoS Pathog (2014) 10(5) e1004067 [RRC reference]

Dudzic JP, Kondo S, Ueda R, Bergman CM, Lemaitre B.
Drosophila innate immunity: regional and functional specialization of prophenoloxidases.
BMC Biol (2015) 13 81 [RRC reference]
Last update 2020-04-03
Research papers using this strain
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