| Strain Information | |
|---|---|
| DGRC Number | 118096 |
| Genotype with FlyBase Link | w[1118]; PGRP-SD[sk1] |
| Genotype | w1118; PGRP-SDsk1 |
| Received Date | 22 Jun 2017 |
| Original Number | PGRP-SD |
| Chromosome | 1;3 |
| Also known as | w;;PGRP-SD SK1 isogenic |
| Original Source | Bruno Lemaitre, École Polytechnique Fédérale de Lausanne |
| Original Comments | Line carries a null mutation in the PGRP-SD gene. The mutation has been isogenized in the w DrosDel background. It shows defect in Imd pathway activation and increases susceptibility to Gram-negative bacteria. |
| Genus | Drosophila |
| Subgenus | Sophophora |
| Species Group | melanogaster |
| Species Subgroup | melanogaster |
| Species | melanogaster |
| Reference | Iatsenko I, Kondo S, Mengin-Lecreulx D, Lemaitre B. PGRP-SD, an Extracellular Pattern-Recognition Receptor, Enhances Peptidoglycan-Mediated Activation of the Drosophila Imd Pathway. Immunity (2016) 45(5) 1013-1023 [RRC reference] |
| Last update | 2023-03-23 |
| Research papers using this strain [Please submit your publication] |
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