Detailed Information [109027]
Strain Information
DGRC Number 109027
Genotype with FlyBase Link w[*]; AGO2[414]
Genotype w*; AGO2414
Received Date 30 June 2004
Also known as w[*]; AGO2414
Original Source Haruhiko Siomi, University of Tokushima
Original Comments AGO2414 allele is a null allele, and homozygous AGO2414 mutants can be maintained as a stock. Homozygous AGO2414 mutant embryos are siRNA-directed RNAi defective, and thus that can be used to study the molecular pathways of RNAi.
References: K
Genus Drosophila
Subgenus Sophophora
Species Group melanogaster
Species Subgroup melanogaster
Species melanogaster
Last update 2017-11-23
Research papers using this strain
[Please submit your publication]
Abe M, Naqvi A, Hendriks GJ, Feltzin V, Zhu Y, Grigoriev A, Bonini NM.
Impact of age-associated increase in 2'-O-methylation of miRNAs on aging and neurodegeneration in Drosophila.
Genes Dev. (2014) 28(1) 44-57 [PubMed ID = 24395246] [RRC reference]
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