microRNA (miRNA) lines

miRNA knockdown collection

Collection of miRNA knockdown mutants that was generated by targeted homologous recombination or P-element excision. This collection includes 91 mutants deleting 123 miRNAs in total.

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Reference

Ya-Wen Chen, Shilin Song, Ruifen Weng, Pushpa Verma, Jan-Michael Kugler, Marita Buescher, Sigrid Rouam, and Stephen M. Cohen (2014) Systematic study of Drosophila microRNA functions using a collection of targeted knockout mutations. Dev. Cell 31: 784--800. DOI: 10.1016/j.devcel.2014.11.029

UAS miRNA collection

Collection of UAS-miRNA constructs that are designed to induce miRNA gene expression under the control of GAL4 drivers. 110 miRNAs or miRNA clusters can be overexpressed using this collection.

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Reference

Sébastien Szuplewski, Jan-Michael Kugler, Sing Fee Lim, Pushpa Verma, Ya-Wen Chen, and Stephen M. Cohen (2012) MicroRNA Transgene Overexpression Complements Deficiency-Based Modifier Screens in Drosophila. Genetics 190: 617--626. DOI: 10.1534/genetics.111.136689


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Last-modified: 06 Nov 2015 (Fri) 14:18:37 (770d)